Creating Impact Together

Progress is built on collective contributions.

Ichnos Sciences is interested in working with collaborators with bold ideas and capabilities that complement and stretch our potential to shift progress, advance science, and deliver transformative medicines. 

We are open to discussing partnerships on our oncology portfolio and have out-licensing opportunities available for our autoimmune disease assets. Explore the pipeline chart below to learn more about these assets and their potential indications.

Interested in partnering or out-licensing? Contact us at Corporate.Communications@ichnossciences.com.

Autoimmune Disease
Candidate Target Preclinical Phase 1 Phase 2 Phase 3 Status
ISB 830 (telazorlimab) OX40 antagonist monoclonal antibody
Atopic Dermatitis (AD)*
      Phase 2b completed†
ISB 880 IL-1RAP antagonist monoclonal antibody
Autoimmune Disease
      IND-Enabling Studies
autoimmune-disease
Compound:
ISB 830 (telazorlimab)
Target:
OX40 antagonist monoclonal antibody
Indication:
Atopic Dermatitis (AD)*
Phase:
phase-2
Status:
Phase 2b completed†
Compound:
ISB 880
Target:
IL-1RAP antagonist monoclonal antibody
Indication:
Autoimmune Disease
Phase:
preclinical
Status:
IND-Enabling Studies

*A US IND for rheumatoid arthritis and other autoimmune indications is active.

†Primary efficacy endpoint (EASI score, % change, baseline to week 16) met at two highest doses tested. Numerical improvements were seen for the two higher-dose arms (300 mg and 600 mg q 2 weeks) of telazorlimab compared to placebo in the secondary endpoints of EASI-75 and Investigator Global Assessment, but the differences were generally not statistically significantly different from placebo.

Note: Assets that were previously identified as GBR XXXX are now identified as ISB XXXX.

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