At Ichnos Sciences, we’re working to make real progress in science and medicine. Explore our recent publications to discover how we’re shifting medicine forward.
|05/13/2020||BEAT® Antibody Engineering Platform||A single mutation increases heavy-chain heterodimer assembly of bispecific antibodies by inducing structural disorder in one homodimer species||Stutz C. et al.||Journal of Biological Chemistry|
|09/12/2019||BEAT® Antibody Engineering Platform||Single-step Protein A and Protein G avidity purification methods to support bispecific antibody discovery and development||Ollier R. et al.||mAbs|
|02/06/2019||ISB 830||GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis||Guttman-Yassky E. et al.||Journal of Allergy and Clinical Immunology|
|04/27/2017||BEAT® Antibody Engineering Platform||Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies||Skegro D. et al.||Journal of Biological Chemistry|
Note: Assets that were previously identified as GBR and GRC are now identified as ISB (for biologics) and ISC (for small molecules), respectively